UNC Lineberger Researchers Identify DNA Repair Enzyme as a Potential Brain Cancer Drug Target

Previous Article Next Article Add to Favorites Contact Information <!– –>Available for logged-in reporters only<!– –> Citations Cell Reports, Dec-2015 Newswise — CHAPEL HILL — Rapidly dividing cells rely on an enzyme called Dicer to help them repair the DNA damage that occurs as they make mistakes in copying their genetic material over and over for new cells. UNC Lineberger Comprehensive Cancer Center researchers have built on the discovery of Dicer’s role in fixing DNA damage to uncover a new potential strategy to kill rapidly dividing, cancerous cells in the brain.In the journal Cell Reports, researchers report that when they removed Dicer from preclinical models of medulloblastoma, a common type of brain cancer in children, they found high levels of DNA damage in the cancer cells, leading to the cells’…


Link to Full Article: UNC Lineberger Researchers Identify DNA Repair Enzyme as a Potential Brain Cancer Drug Target