Study finds genetic convergence between cognition and neurodevelopmental disorders

Singapore, Dec. 22, 2015 – For the first time, a study has demonstrated a genetic convergence between cognition and neurodevelopmental disorders in the human brain. These findings, published online in Nature Neuroscience on Dec. 21, 2015 2015, provide an alternate starting point for scientists to develop therapies for such disorders.A team of researchers from Duke-NUS Medical School (Duke-NUS) and Imperial College London (ICL) identified a network of genes in the brain that regulates normal cognitive abilities. This network is also linked to a range of neurodevelopmental disorders, such as autism, epilepsy, intellectual disability and schizophrenia. In many neurodevelopmental disorders, the impairment of cognitive abilities is reported to be a core clinical feature. However, no explanation had been provided for this association, until now. The Duke-NUS and ICL team began their…


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