Rhythm of oscillations in cerebral cortex, key to understanding Down syndrome

IMAGE: Inhibitory neuron activity (green) is controlled by inhibitory contacts (red). This control is not properly regulated in the cerebral cortex of the mice model for Down syndrome. view more This news release is available in Spanish. Scientists at the Centre for Genomic Regulation (CRG) and August Pi i Sunyer Biomedical Research Institute (IDIBAPS) have made a first-ever identification of the alterations in the neuronal circuit that impact cerebral cortex physiology, and that could be the cause of cognitive deficits in Down Syndrome. The study, published in the latest edition of the Journal of Neuroscience, explains how a gene linked to Down Syndrome is associated with altered oscillations in the cerebral cortex, the region responsible for our capacity for reasoning, language and social behavior. Barcelona, April 5, 2016. Cerebral activity is…


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