Rat study reveals long-term effects of adolescent amphetamine abuse on the brain

IMAGE: Psychology professor Joshua Gulley, left, graduate student Shuo Kang and their colleagues found that amphetamine abuse in young rats led to changes in dopamine signaling in the brain that persisted… view more Credit: Photo by L. Brian Stauffer CHAMPAIGN, Ill. — A study of rats given regular, high doses of amphetamine finds that those exposed to the drug at an age corresponding to human adolescence experience long-term changes in brain function that persist into adulthood. The study, reported in the journal Neuroscience, found that amphetamine leads to changes in dopamine signaling. Dopamine is a neurotransmitter that plays a role in memory, attention, learning and feelings of pleasure. “The dopamine system, which continues to develop throughout adolescence and young adulthood, is a primary target of psychostimulant drugs like amphetamine,” said University…


Link to Full Article: Rat study reveals long-term effects of adolescent amphetamine abuse on the brain