Potential Solution Offered to Reduce Side Effects of Immunotherapy in Alzheimer’s Treatment

Southampton, UK (Scicasts) — It is estimated that 46.8 million people worldwide are living with dementia, with Alzheimer’s disease the most common form. Now researchers from the University of Southampton have discovered a possible solution for side effects seen in immunotherapy treatment for Alzheimer’s. Immunotherapy is a promising strategy for the treatment of Alzheimer’s that uses antibodies to stimulate the immune system to remove pieces of a protein called amyloid beta which accumulates in the brain (in deposits known as plaques) and is thought to be a major factor driving Alzheimer’s neurodegenerative effects. Antibodies directed against amyloid beta have been able to successfully clear plaques and reverse cognitive deficits in mouse models. However, despite this success, clinical trials using these antibodies caused inflammatory side effects in the brain of Alzheimer’s…


Link to Full Article: Potential Solution Offered to Reduce Side Effects of Immunotherapy in Alzheimer’s Treatment