Other articles by Grahame J. Kidd on PubMed

 JoVE Neuroscience Konark Mukherjee1, Helen R. Clark1, Vrushali Chavan1, Emily K. Benson2, Grahame J. Kidd2, Sarika Srivastava1 1Virginia Tech Carilion Research Institute, 2Renovo Neural Incorporated JoVE 54214 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2002  |  Pubmed ID: 11826117 Transgenic mice expressing enhanced green fluorescent protein (EGFP) driven by the mouse myelin proteolipid protein (PLP) gene promoter have been developed to investigate cells in the oligodendrocyte lineage. Transgene expression is consistent with the developmental expression of PLP, with cells at all stages of oligodendrocyte differentiation clearly visualized. These animals were analyzed to establish the time course of oligodendrocyte progenitor migration, proliferation, and differentiation in neonatal cortex. In these animals, two populations of NG2 proteoglycan-positive oligodendrocyte progenitor cells were identified that exist in postnatal subventricular zone…


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