Optical approach for screening toxins mimics mammal senses

Researchers at the University of Leicester, UK, have developed a new photonics-based approach for analyzing toxic chemicals in complex samples that mimics the way mammals smell and taste. The scientists say that the technique could reduce the need for testing on laboratory animals in biomedical research and other areas of chemical testing. In the study, recently published in Nature’s Scientific Reports, a fluorescent assay combines a mixture of environmental-sensitive fluorescent dyes and human skin cells that generate fluorescence spectra patterns distinctive for particular physiological conditions. Using multivariate data analysis, the optical signal is further processed, providing qualitative information and fast diagnostics. ’Electronic nose’ The study was inspired by the operating principle of the “electronic noses and tongues” systems, which mimic mammalian smell and taste recognition, combining semi-specific sensors and chemometric…


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