New UW model helps zero in on harmful genetic mutations

October 22, 2015 A new UW model can help narrow down which genetic mutations affect how genes splice and contribute to disease. In this illustration, the cell’s splicing machinery is trying to pick which “cutting” sites (pictured as white flags) it should use.Jennifer Sunami Between any two people, there are likely to be at least 10 million differences in the genetic sequence that makes up their DNA. Most of these differences don’t alter the way cells behave or cause health problems. But some genetic variations greatly increase the likelihood that a person will develop cancer, diabetes, colorblindness or a host of other diseases. Despite rapid advances in our ability to map an individual’s genome — the precise coding that makes up his or her genes — we know much less…


Link to Full Article: New UW model helps zero in on harmful genetic mutations

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