CRISPR/Cas9 Guide RNA Design Tools Incorporate New Rules for On-Target Activity

NEW YORK (GenomeWeb) – A new algorithm for calculating on-target guide RNA efficiency is taking off in the field, both in home-grown and commercial CRISPR/Cas9 experiment design software. The fruit of a collaboration between scientists at the Broad Institute and machine learning experts at Microsoft Research, the algorithm has uncovered new rules and considerations for how well a single guide RNA (sgRNA) will work for gene knock-down experiments, with results that can be broadly applied. Get the full story withGenomeWeb Premium Only $95 for thefirst 90 days* A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story. Try GenomeWeb Premium now. Already a GenomeWeb Premium member? Login Now.Or, See if your institution qualifies for premium…


Link to Full Article: CRISPR/Cas9 Guide RNA Design Tools Incorporate New Rules for On-Target Activity