Chronic Ampakine Treatments Stimulate Dendritic Growth and Promote Learning in Middle-Aged …

Julie C. Lauterborn1,*, Linda C. Palmer1,*, Yousheng Jia1, Danielle T. Pham1, Bowen Hou1, Weisheng Wang1, Brian H. Trieu1, Conor D. Cox1, Svetlana Kantorovich1, Christine M. Gall1,2,*, and Gary Lynch1,3,* 1Department of Anatomy and Neurobiology, 2Department of Neurobiology and Behavior, and 3Department of Psychiatry and Human Behavior, University of California, Irvine, California 92697 Author contributions: J.C.L., L.C.P., Y.J., D.T.P., B.H., W.W., B.H.T., C.D.C., C.M.G., and G.L. designed research; J.C.L., L.C.P., Y.J., D.T.P., B.H., W.W., B.H.T., C.D.C., S.K., and G.L. performed research; J.C.L., L.C.P., Y.J., D.T.P., B.H., W.W., B.H.T., C.D.C., S.K., C.M.G., and G.L. analyzed data; J.C.L., L.C.P., D.T.P., C.D.C., C.M.G., and G.L. wrote the paper. ↵*J.C.L., L.C.P., C.M.G., and G.L. contributed equally to this work. Abstract Positive allosteric modulators of AMPA-type glutamate receptors (ampakines) have been shown to rescue synaptic plasticity…


Link to Full Article: Chronic Ampakine Treatments Stimulate Dendritic Growth and Promote Learning in Middle-Aged …