Alzheimer’s Sleep Memory Formation Disturbed By Protein Deposits

October 23, 2015Share this article: Alzheimer’s Sleep Memory Formation Disturbed By Protein Deposits Researchers from the Technical University of Munich (TUM) have shown that protein deposits in the brains of Alzheimer’s patients, known as beta-amyloid plaques, disturb memory formation during sleep. The results are published in Nature Neuroscience. In “normal” sleeping brains, slow waves, known as slow oscillations, help consolidate what has been learned and shifts memories into long-term storage. The waves are formed in the brain’s cortex through a network of nerve cells, and are then spread out into other parts of the brain such as the hippocampus. However, this process is disturbed in Alzheimer’s disease. In their study, Marc Aurel Busche, MD, PhD, from the Department of Psychiatry and Psychotherapy at TUM University Hospital Klinikum and TUM Institute…


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