A small dose of E. coli wall has big impact on the sweet tooth

Dr. Lynnette McCluskey, neuroscientist in the Department of Neuroscience and Regenerative Medicine at the Medical College of Georgia at Augusta University. Credit: Phil Jones Putting just a tiny piece of the wall of detoxified E. coli into their gut make mice lose their natural sweet tooth, researchers report. Fifteen hours after one small dose is placed in the gut, levels of the satiety hormone leptin go up, and within seven days, the taste for sweets and the number of sweet receptors on the tongue, go way down, said Dr. Lynnette McCluskey, neuroscientist in the Department of Neuroscience and Regenerative Medicine at the Medical College of Georgia at Augusta University. Mice remain in good health with their taste for other foods, such as salty ones, intact, said McCluskey who presents the…


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