A common NTRK2 variant is associated with emotional arousal and brain white-matter integrity in …

Citation: Translational Psychiatry (2016) 6, e758; doi:10.1038/tp.2016.20Published online 15 March 2016K Spalek1,2, D Coynel1,2, V Freytag1,2, F Hartmann1,2, A Heck2,3, A Milnik2,3, D de Quervain1,3 and A Papassotiropoulos2,3,4 Top of page Introduction A dysregulation of emotional processes is commonly observed in many psychiatric disorders. Specifically, more than 75% of psychiatric diagnostic categories are characterized by emotional dysregulation.1 In some psychiatric disorders, like mood or anxiety disorders, emotional dysregulation is one of the core symptoms giving rise to the respective diagnosis.1 The International Affective Picture System (IAPS),2 which consists of a large set of standardized, emotion-evoking photographs covering a wide range of semantic categories, is often used in experimental studies to test and quantify emotional processes. Typically, subjects are asked to rate these pictures on two emotion dimensions, namely valence (ranging from pleasant to unpleasant) and arousal (ranging from calm to…


Link to Full Article: A common NTRK2 variant is associated with emotional arousal and brain white-matter integrity in …